Monday, August 24, 2009

Keratin Debris Under Nails




WELCOME


_______________________

UNIVERSITY OF GUADALAJARA

CURRENT COURSE SCHEDULE FOR 2008 CALENDAR SUBJECT TO NAME



CELL BIOLOGY

SUBJECT CODE
101 CELL AND MOLECULAR BIOLOGY DEPARTMENT CODE DEPARTMENT
BC
Cinci UNIVERSITY OF AGRICULTURAL BIOLOGICAL AND LOAD TIME 93 Hours
THEORY, PRACTICE
12 hours Total 105 10 CREDITS

VOCATIONAL TRAINING LEVEL PREREQUISITES BS Biochemistry
GOAL




study the cell as the fundamental unit COMPOSITION, STRUCTURE AND FUNCTION OF LIVING FOR ESTABLISHING THE BASIS FOR THE UNDERSTANDING OF THE PHYSIOLOGY OF BIOLOGICAL SYSTEMS



SPECIFIC OBJECTIVES 1. Identify the purpose of studying cell biology and its features, its scope and relationship to other areas of knowledge.

2. Knowing how prebiotic and processes that have led to levels of cellular organization now known, differentiating cells of prokaryotes eukaryotic cells both plant and animal.

3. Study the principles that govern the formation and function of biological membranes from its components, as well as transport mechanisms through membranes.

4. Studying the structure of intracellular organelles, integrating biochemical knowledge of metabolism with the function and structure of them.

5. Understanding the mechanisms that allow inter-and intracellular communication.

6. Understanding the mechanisms by which preserves and transmits the biological information.


THEMATIC CONTENT SYNTHETIC

conceptual units

1. INTRODUCTION TO THE STUDY OF THE CELL. hours: 4 Hrs.

1.1. DEFINITION AND SCOPE OF CELL BIOLOGY
(and its relation to other areas)
1.2 Levels of biological organization
1.3 Characteristics of living matter and cellular theory
1.4 Features of prokaryotes and eukaryotes
1.5 TECHNIQUES USED IN CELL BIOLOGY

2. ORIGIN AND EVOLUTION OF THE CELL. hours: 6 Hrs.

2.1 Historical background (Various theories)
2.2 STAGES OF THE ORIGIN OF LIFE

2.2.1 Abiotic Stage (Theory of Evolution Chemical Oparin and Haldane)

2.2.1.1 Origin and formation of the universe.
2.2.1.2 Origin and formation of the earth. Training
air and primeval soup
Synthesis of monomers and polymers (Miller, Urey, Wachterhauser and others)

Stage 2.2.2 Prebiotic Evolution (protobiological)

2.2.2.1 pre-RNA world (metabolic systems vs. self-replicating systems) 2.2.2.2
RNA World (autocatalytic systems, self-replicating and inheritable) Models 2.2.2.3
prebiotics (protobiont, sulfobios, microspherules protein and coacervates)

Stage 2.2.3 Biological Evolution (biological)

2.2.3.1 In prokaryotes to eukaryotes: compartmentalization and endosymbiosis. Food
: heterotrophs vs. autotrophs.
Metabolism: Aerobic vs. Anaerobic
Power: Photosynthetic
Chemosynthetic
vs 3. Cell membranes. hours: 20 Hrs

3.1. STRUCTURE, COMPOSITION AND FUNCTIONS OF THE PLASMA MEMBRANE

3.1.1 Structure and chemical composition (membrane structure models)

3.1.1.1 Properties: semipermeable Asymmetry, fluidity, elasticity and resistance to stress.

3.1.2 Functions of the membrane. 3.1.3 Specializations


membrane junctions
3.1.3.1 (strong, adherent and communicating)
3.1.3.2 Receivers (plasma membrane and intracellular)
3.1.4 Extracellular matrix and cell wall

3.2. Membrane transport mechanism

3.2.1 Through Membrane Transport

3.2.1.1 Passive Diffusion

simple
Σ Σ Osmosis: hypotonic, isotonic, hypertonic. Σ
Facilitated diffusion: permeases, ion channels

3.2.1.2 Active Transport
Σ
by Co-transporters Unidirectional

Exchange Σ Σ Bi ion pumps

3.2.2 By

3.2.2.1 Endocytosis Vesicles


Σ Σ Pinocytosis Receptor-mediated endocytosis Phagocytosis


Σ 3.2.2.3 Exocytosis

4. INTRACELLULAR ORGANIZATION. hours: 32 Hrs. 4.1

endomembrane system and intracellular organelles



Core 4.1.1 Structural Components (nuclear envelope, nuclear matrix, chromatin) and complex
supramacromolecular
Nucleosome

functions (replication and transcription)



4.1.2 Smooth endoplasmic reticulum: Rugged
lipid synthesis, protein synthesis and complex
supramacromolecular
Ribosome 4.1.3


Golgi complex protein modification
Vesicle formation

vesicles System 4.1.4 Lysosomes


microbodies (peroxisomes, glyoxysomes, glycosomes, hydrogenosomes)

storage vesicles Vesicles secretion granules




4.1.6 4.1.5 Mitochondria Chloroplasts

4.2. CYTOSKELETON AND MATRIX Cytoplasmic

4.2.1 4.2.2 Microtubule System

microtrabecular microtubule organizing center and complex
supramacromoleculares Centrioles and Basal Bodies and Flagella Cilia
of prokaryotes and eukaryotes. 4.2.3

Microfilaments actin and myosin

nonmuscle cells
sarcomere structure and muscle contraction

4.2.4 Intermediate Filaments


5. CELL COMMUNICATION. hours: 16 Hrs.

5.1 BASICS OF CELLULAR COMMUNICATION
Issuer, Message, Medium, Receiver and Response
INTERCELLULAR
5.2 Communication



5.2.1 Characteristics 5.2.2 Examples: Communication

endocrine, autocrine, paracrine
neuron-neuron communication, neuron-muscle cell, neuron-cell secretory intracellular communication


5.3

5.3.1 System Components 5.3.2
Examples: Via cAMP; Way of DAG and IP3, and others.

6. CELL CYCLE . Hours: 15 hrs .



6.1 Concept 6.2 STAGES OF CELL

Phases 6.2.1: M, G1, S, G2, G0.

6.2.2 Cell division (M phase) 6.2.2.1
Eukaryotes: Mitosis, Meiosis.

6.2.2.2 Prokaryotes: binary fission, sporulation

6.3
cell cycle regulation
inducers and repressors Factors 6.3.1.


LABORATORY PRACTICE

1. Formation of coacervates.
2. Cell differentiation prokaryotes and eukaryotes (animal and plant)
3. Transport through membrane (osmosis).
4. Isolation of chloroplasts.
5. Mitosis. BASIC BIBLIOGRAPHY



1) Molecular Biology of the Cell. Alberts. 3a. ed. 2002. Garland
2) Cell Biology. Wood, Smith. 1a. ed. 2006. Addison Wesley
3) Cell Biology Avers, Ch 2a. ed. 2002. Grupo Editorial Iberoamericano.
4) Cellular Physiology. Giese, AE 4a. ed. 1999. American.
5) Cell and Molecular Biology. Robertis and Robertis. 10a. ed. 1999. El Ateneo.
6) Cell Biology. Junqueira, et al. 1a. 5a. Reprinted 1990. Mexican Medical Press.
7) Cellular Biology. Gerald Karp. American / McGraw Hill. 1999
8) The Cell, A Molecular Approach, Cooper GM "2nd Ed 2000. ADM PRESS
9) Molecular Cell Biology. Lodish, H. ET. AL. 2000. Freeman.



SUPPLEMENTARY BIBLIOGRAPHY 1. The Origin Life. Lazcano-Araujo, A. Ed. Trillas, 1990.
2. Molecular Biology of the Gen. Watson, J. 4a. ed. 1987. The Benjamin / Cummings Publishing Co, Inc.
3. The living cell. De Duve, A. 1992. Scientific American Library. Scientific Press.
4. Biochemistry. Leningher, A. 2a. ed. 1980. Omega.
5. Biology. Solomon, Ville, et al. 2a. ed. 1992. McGraw Hill-Interamericana.
6. Histology. Weiss, L. & Greep. 4a. ed. 1977. McGraw Hill.
TEACHING-LEARNING


In a theoretical-practical, such as this, the transmission of subject content is the responsibility of the teacher, student and reference literature and materials properly programmed and method transfer of matter to the laboratory or field work.

One idea is to unify the classroom, laboratory and field, creating a course designed teaching aids "on purpose" under the scheme: Reading - research presentation - discussion, demonstration - Exercises - practice - testing, evaluation - measurement - Accreditation - promotion. This model seeks flexible learning mode to carry out a continuous upward development of school learning.

FEATURES OF THE IMPLEMENTATION OF THE SUBJECT BUSINESS

common basic matter, relevant for students of Biology, Agronomy, and Veterinary Medicine, which sets the stage for understanding the functioning of biological systems.

KNOWLEDGE, SKILLS, VALUES, ETC.

With the development of the course, it is intended that students acquire skills and abilities allowing him to identify the importance of the cell as the fundamental unit of living things



Evaluation methods Evaluation of Teacher (ordinary and extraordinary course) Reviews
theoretical partial participation and attendance

presentations
analysis and discussion of reading questions and answers


Product Practices
terminal Departmental Review (Value 10% of final grade)

PARTICIPATION IN CLASS 10%
exams
40% 10% departmental review

PRACTICES 10% 30% TASKS


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